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Infectious Disease

Infectious diseases, spread by viruses, bacteria and parasites, have shaped human history more than most wars. John M. Barry's The Great Influenza tells the story of the deadliest of modern pandemics, the influenza of 1918, which spread with soldiers in the last months of the First World War and killed tens of millions. Barry follows the scientists who fought it and shows how secrecy and political choices made it worse. A classic of medical history, essential for understanding pandemics past and future. See Health & Medicine for more.

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The Great Influenza

The Epic Story of the Deadliest Plague in History

By John M. Barry

John M. Barry’s The Great Influenza is a history of the 1918–1919 influenza pandemic, with particular attention to the United States. It follows the disease through military camps, cities, hospitals, laboratories, and public institutions while explaining why a modernizing society proved so vulnerable. Barry places the catastrophe within two intertwined stories: the transformation of American medical education and research, and the pressures created by World War I. Scientists struggled to identify an agent they could not yet see, physicians faced overwhelming numbers of patients without antiviral drugs or antibiotics, and officials often subordinated candid public communication to wartime priorities. The result is more than a chronicle of mass illness. It is an examination of scientific uncertainty, institutional capacity, political leadership, and public trust—forces that shape whether societies can recognize and contain a fast-moving emergency.

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